Development and Functional Characterization of a Blood-Brain Barrier Model on a Chip for Predictive Drug Permeability Testing

Authors

DOI:

https://doi.org/10.26754/jji-i3a.202613357

Abstract

The blood-brain barrier remains a critical challenge in CNS drug development. This work presents the preliminary development and characterization of a microfluidic BBB-on-a-chip model, comparing monoculture and triculture configurations against traditional Transwell systems. Additionally, real time monitoring of fundamental metabolites is being implemented.

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Published

2026-07-17

Issue

Vol. 14 (2026): Actas de la XV Jornada de Jóvenes Investigadores e Investigadoras del I3A - 9 de junio de 2026

Section

Artículos (Ingeniería Biomédica)

License

Copyright (c) 2026 Celia Ferrando Martin, Beatriz Sanz, Sandra González-Lana, Ignacio Ochoa, Rosa Monge, Sara Oliván

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

Ferrando-Martín, C., Sanz, B., González-Lana, S., Ochoa, I., Monge, R., & Oliván, S. (2026). Development and Functional Characterization of a Blood-Brain Barrier Model on a Chip for Predictive Drug Permeability Testing. Jornada De Jóvenes Investigadores Del I3A, 14. https://doi.org/10.26754/jji-i3a.202613357