Development and Functional Characterization of a Blood-Brain Barrier Model on a Chip for Predictive Drug Permeability Testing
DOI:
https://doi.org/10.26754/jji-i3a.202613357Resumen
The blood-brain barrier remains a critical challenge in CNS drug development. This work presents the preliminary development and characterization of a microfluidic BBB-on-a-chip model, comparing monoculture and triculture configurations against traditional Transwell systems. Additionally, real time monitoring of fundamental metabolites is being implemented.
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Publicado
2026-07-17
Número
Sección
Artículos (Ingeniería Biomédica)
Licencia
Derechos de autor 2026 Celia Ferrando Martin, Beatriz Sanz, Sandra González-Lana, Ignacio Ochoa, Rosa Monge, Sara Oliván
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.
Cómo citar
Ferrando Martin, C., Sanz, B., González-Lana, S., Ochoa, I., Monge, R., & Oliván, S. (2026). Development and Functional Characterization of a Blood-Brain Barrier Model on a Chip for Predictive Drug Permeability Testing. Jornada De Jóvenes Investigadores Del I3A, 14. https://doi.org/10.26754/jji-i3a.202613357
